LCLS takes X-ray snapshots of atoms and molecules at work, revealing fundamental processes in materials, technology and living things. Its snapshots can be strung together into movies that show chemical reactions as they happen.
Hundreds of scientists each year conduct groundbreaking experiments into the fundamental processes of chemistry, materials and energy science, biology and technology at LCLS. Its experiments generated more than 600 articles in peer-reviewed scientific publications in the first six years of operation, with almost a quarter of them appearing in prominent journals like Science and Nature.
New Extremes for X-ray Science
Pulses are fired about 120 pulses per second, each one lasting just quadrillionths of a second, or "femtoseconds"—a timescale at which the motion of atoms can be seen and tracked. The pulses allow scientists to study important proteins at room temperature, in some cases even while they are active.
LCLS creates X-ray pulses a billion times brighter than previously available at synchrotrons.
Already, LCLS has enabled scientists to uncover the 3-D molecular structure of an enzyme involved in the transmission of African sleeping sickness, to study how a new type of painkiller with potentially reduced side effects interacts with a specialized protein that regulates the body’s pain response, to obtain live snapshots of steps during the water-splitting reaction in photosynthesis, and to study the microscopic components of air pollution at the nanoscale.
Scientists have been able to measure shock waves in metals heated to millions of degrees. At the other extreme, LCLS has provided a first glimpse of the structure of supercooled water, which remains liquid well below its normal freezing temperature, and opened a new window into tiny quantum tornadoes, which form in fast-spinning droplets of supercooled liquid helium.
A Broad Reach
LCLS is enabling pioneering research across many fields:
Harnessing the Sun’s Light
Photosynthesis is one of the most important chemical reactions on Earth, yet most aspects are not fundamentally understood. With LCLS, researchers can directly observe the natural processes that convert the sun’s light into usable energy, with promising implications for America’s energy future.
Revealing Life's Secrets & Aiding Drug Development
Scientists are using LCLS to determine the structures of proteins from tiny nanocrystals. This unique capability opens the door to studying tens of thousands of biological structures that were out of reach before, including proteins important in disease and its treatment. LCLS has enabled detailed structural studies of membrane proteins, which are key targets for drug discovery; its unique pulses offer important advantages over more conventional X-ray sources in advancing membrane protein research.
Developing Future Electronics
Experiments at LCLS are exploring new ways to design and control the magnetic and electronic properties of electronic materials with ultrashort pulses of light. This could ultimately lead to extremely fast, low-energy computer memory chips and data-switching devices.
Designing New Materials and Exploring Fusion
LCLS gives scientists the right tools to investigate, as never before possible, the extremely hot, dense matter at the centers of stars and giant planets. These experiments help researchers explore how materials respond to stress, design new materials with enhanced properties, and attempt to replicate the nuclear fusion process that powers the sun.
Customizing Chemical Reactions
Research at LCLS is improving our understanding of the earliest steps in chemical reactions, including catalytic reactions that are critical in producing fuels and other industrial chemicals. This improved understanding of ultrafast chemistry at the scale of atoms and molecules could lead to more efficient and controllable chemical reactions.
How It Works
LCLS was the first laser in the world, and one of just two now in operation, to produce "hard," or very-high-energy X-rays. The process of producing X-ray pulses starts in a section of SLAC's linear accelerator.
First a drive laser generates a precise pulse of ultraviolet light, which travels to an injector "gun" and strikes the surface of a copper plate. The plate responds by releasing a burst of electrons, which are accelerated by a series of devices to boost their energy.
The electron pulses then enter the LCLS Undulator Hall, the heart of LCLS, where they are put to work generating X-ray laser light.
The Undulator Hall houses thousands of special magnets, spaced a few millimeters apart and arrayed so their north-south magnetic poles alternate. The poles alternately attract and repel passing electron bunches, which swerve back and forth in an undulating motion that forces them to give off X-rays.
As each electron bunch travels with its associated X-rays, they start to interact with each other. The electrons arrange themselves in parallel sheets; this causes the waves of X-ray light to line up so their crests and troughs match, creating “coherent” or laser light and greatly boosting the power of the X-ray pulses. At this point the electrons are no longer needed; they are safely discarded, and the X-ray laser pulses continue in a straight line to LCLS experiments, arriving at a rate of up to 120 pulses per second.
X-rays are delivered to any of seven specialized experimental stations, and in some cases to multiple stations simultaneously. Each station has a dedicated team of scientists and support staff who spearhead R&D efforts, engage in innovative research and assist users with experiments.
Each station is equipped with a suite of instruments that use specialized techniques to gather data, from telltale signatures of electrons and ions to the intricate patterns left by crystallized samples struck by the X-ray laser.
The scientific advancements at LCLS have garnered worldwide attention, and work has begun on a revolutionary new tool, LCLS-II. The new capabilities provided by LCLS-II’s increased repetition rate and energy range will allow scientists to study how light triggers chemical reactions in gases and physical changes in materials. They will also allow study of the high-resolution structure of matter under extreme conditions, such as high pressures and high temperatures.
With LCLS-II, SLAC will continue to advance the frontiers of X-ray research, keeping the United States at the forefront of this very competitive international arena and supporting transformational science for the coming decade.
In addition to delivering the upgraded facility, SLAC will continue to pursue an integrated and focused R&D program to maximize the scientific impact of LCLS-II and to prepare for future facilities.
Find Out More about LCLS
The world at the atomic scale is never at rest, with particles moving so quickly and molecular bonds changing so rapidly that we have been unable to capture their motion directly until now.
A particle accelerator's $1 billion upgrade could lead to improvements in electronic gear. Also in SLAC's sights: better batteries and cancer treatments.
Explore femtosecond science at SLAC through interactive infographic, videos, Q & A with scientists, virtual tours of LCLS, etc.